Results
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1.
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Inhibitors of the hepatitis C virus NS3 protease with basic amine functionality at the P3-amino acid N-terminus: discovery and optimization of a new series of P2-P4 macrocycles. [electronic resource] by
- Harper, Steven
- Ferrara, Marco
- Crescenzi, Benedetta
- Pompei, Marco
- Palumbi, Maria Cecilia
- DiMuzio, Jillian M
- Donghi, Monica
- Fiore, Fabrizio
- Koch, Uwe
- Liverton, Nigel J
- Pesci, Silvia
- Petrocchi, Alessia
- Rowley, Michael
- Summa, Vincenzo
- Gardelli, Cristina
Producer: 20090921
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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2.
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Biochemical and cell-based assays for characterization of BACE-1 inhibitors. [electronic resource] by
- Pietrak, Beth L
- Crouthamel, Ming-Chih
- Tugusheva, Katherine
- Lineberger, Janet E
- Xu, Min
- DiMuzio, Jillian M
- Steele, Thomas
- Espeseth, Amy S
- Stachel, Shawn J
- Coburn, Craig A
- Graham, Samuel L
- Vacca, Joseph P
- Shi, Xiao-Ping
- Simon, Adam J
- Hazuda, Daria J
- Lai, Ming-Tain
Producer: 20051011
In:
Analytical biochemistry vol. 342
Availability: No items available.
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3.
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Discovery of MK-1220: A Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure. [electronic resource] by
- Rudd, Michael T
- McCauley, John A
- Butcher, John W
- Romano, Joseph J
- McIntyre, Charles J
- Nguyen, Kevin T
- Gilbert, Kevin F
- Bush, Kimberly J
- Holloway, M Katharine
- Swestock, John
- Wan, Bang-Lin
- Carroll, Steven S
- DiMuzio, Jillian M
- Graham, Donald J
- Ludmerer, Steven W
- Stahlhut, Mark W
- Fandozzi, Christine M
- Trainor, Nicole
- Olsen, David B
- Vacca, Joseph P
- Liverton, Nigel J
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 2
Availability: No items available.
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4.
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MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants. [electronic resource] by
- Summa, Vincenzo
- Ludmerer, Steven W
- McCauley, John A
- Fandozzi, Christine
- Burlein, Christine
- Claudio, Giuliano
- Coleman, Paul J
- Dimuzio, Jillian M
- Ferrara, Marco
- Di Filippo, Marcello
- Gates, Adam T
- Graham, Donald J
- Harper, Steven
- Hazuda, Daria J
- Huang, Qian
- McHale, Carolyn
- Monteagudo, Edith
- Pucci, Vincenzo
- Rowley, Michael
- Rudd, Michael T
- Soriano, Aileen
- Stahlhut, Mark W
- Vacca, Joseph P
- Olsen, David B
- Liverton, Nigel J
- Carroll, Steven S
Producer: 20130212
In:
Antimicrobial agents and chemotherapy vol. 56
Availability: No items available.
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5.
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Discovery of vaniprevir (MK-7009), a macrocyclic hepatitis C virus NS3/4a protease inhibitor. [electronic resource] by
- McCauley, John A
- McIntyre, Charles J
- Rudd, Michael T
- Nguyen, Kevin T
- Romano, Joseph J
- Butcher, John W
- Gilbert, Kevin F
- Bush, Kimberly J
- Holloway, M Katharine
- Swestock, John
- Wan, Bang-Lin
- Carroll, Steven S
- DiMuzio, Jillian M
- Graham, Donald J
- Ludmerer, Steven W
- Mao, Shi-Shan
- Stahlhut, Mark W
- Fandozzi, Christine M
- Trainor, Nicole
- Olsen, David B
- Vacca, Joseph P
- Liverton, Nigel J
Producer: 20100504
In:
Journal of medicinal chemistry vol. 53
Availability: No items available.
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6.
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Development of potent macrocyclic inhibitors of genotype 3a HCV NS3/4A protease. [electronic resource] by
- Rudd, Michael T
- McCauley, John A
- Romano, Joseph J
- Butcher, John W
- Bush, Kimberly
- McIntyre, Charles J
- Nguyen, Kevin T
- Gilbert, Kevin F
- Lyle, Terry A
- Holloway, M Katharine
- Wan, Bang-Lin
- Vacca, Joseph P
- Summa, Vincenzo
- Harper, Steven
- Rowley, Michael
- Carroll, Steven S
- Burlein, Christine
- DiMuzio, Jillian M
- Gates, Adam
- Graham, Donald J
- Huang, Qian
- Ludmerer, Steven W
- McClain, Stephanie
- McHale, Carolyn
- Stahlhut, Mark
- Fandozzi, Christine
- Taylor, Anne
- Trainor, Nicole
- Olsen, David B
- Liverton, Nigel J
Producer: 20130423
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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7.
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Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2-P4 linkers. [electronic resource] by
- Rudd, Michael T
- McIntyre, Charles J
- Romano, Joseph J
- Butcher, John W
- Holloway, M Katharine
- Bush, Kimberly
- Nguyen, Kevin T
- Gilbert, Kevin F
- Lyle, Terry A
- Liverton, Nigel J
- Wan, Bang-Lin
- Summa, Vincenzo
- Harper, Steven
- Rowley, Michael
- Vacca, Joseph P
- Carroll, Steven S
- Burlein, Christine
- DiMuzio, Jillian M
- Gates, Adam
- Graham, Donald J
- Huang, Qian
- Ludmerer, Steven W
- McClain, Stephanie
- McHale, Carolyn
- Stahlhut, Mark
- Fandozzi, Christine
- Taylor, Anne
- Trainor, Nicole
- Olsen, David B
- McCauley, John A
Producer: 20130423
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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8.
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P2-quinazolinones and bis-macrocycles as new templates for next-generation hepatitis C virus NS3/4a protease inhibitors: discovery of MK-2748 and MK-6325. [electronic resource] by
- Rudd, Michael T
- Butcher, John W
- Nguyen, Kevin T
- McIntyre, Charles J
- Romano, Joseph J
- Gilbert, Kevin F
- Bush, Kimberly J
- Liverton, Nigel J
- Holloway, M Katharine
- Harper, Steven
- Ferrara, Marco
- DiFilippo, Marcello
- Summa, Vincenzo
- Swestock, John
- Fritzen, Jeff
- Carroll, Steven S
- Burlein, Christine
- DiMuzio, Jillian M
- Gates, Adam
- Graham, Donald J
- Huang, Qian
- McClain, Stephanie
- McHale, Carolyn
- Stahlhut, Mark W
- Black, Stuart
- Chase, Robert
- Soriano, Aileen
- Fandozzi, Christine M
- Taylor, Anne
- Trainor, Nicole
- Olsen, David B
- Coleman, Paul J
- Ludmerer, Steven W
- McCauley, John A
Producer: 20151216
In:
ChemMedChem vol. 10
Availability: No items available.
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9.
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Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor. [electronic resource] by
- Harper, Steven
- McCauley, John A
- Rudd, Michael T
- Ferrara, Marco
- DiFilippo, Marcello
- Crescenzi, Benedetta
- Koch, Uwe
- Petrocchi, Alessia
- Holloway, M Katharine
- Butcher, John W
- Romano, Joseph J
- Bush, Kimberly J
- Gilbert, Kevin F
- McIntyre, Charles J
- Nguyen, Kevin T
- Nizi, Emanuela
- Carroll, Steven S
- Ludmerer, Steven W
- Burlein, Christine
- DiMuzio, Jillian M
- Graham, Donald J
- McHale, Carolyn M
- Stahlhut, Mark W
- Olsen, David B
- Monteagudo, Edith
- Cianetti, Simona
- Giuliano, Claudio
- Pucci, Vincenzo
- Trainor, Nicole
- Fandozzi, Christine M
- Rowley, Michael
- Coleman, Paul J
- Vacca, Joseph P
- Summa, Vincenzo
- Liverton, Nigel J
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 3
Availability: No items available.
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