Rational application of targeted therapeutics in mucinous colon/appendix cancers with positive predictive factors. [electronic resource]
Producer: 20210423Description: 1753-1767 p. digitalISSN:- 2045-7634
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Appendiceal Neoplasms -- genetics
- Appendix -- cytology
- Cell Line, Tumor
- Chemotherapy, Adjuvant -- methods
- Colon -- cytology
- Colonic Neoplasms -- genetics
- Drug Synergism
- Endoplasmic Reticulum Chaperone BiP
- Female
- Humans
- Indazoles -- pharmacology
- Intestinal Mucosa -- cytology
- Mice
- Mitogen-Activated Protein Kinase Kinases -- antagonists & inhibitors
- Molecular Targeted Therapy -- methods
- Mucin-2 -- metabolism
- Mutation
- Neoplasms, Cystic, Mucinous, and Serous -- genetics
- Phosphatidylinositol 3-Kinases -- metabolism
- Primary Cell Culture
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins p21(ras) -- genetics
- Pyridones -- pharmacology
- Pyrimidinones -- pharmacology
- Sulfonamides -- pharmacology
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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