Disease-linked mutations in the phosphatidylcholine regulatory enzyme CCTα impair enzymatic activity and fold stability. [electronic resource]
Producer: 20190520Description: 1490-1501 p. digitalISSN:- 1083-351X
- Animals
- COS Cells
- Catalysis
- Catalytic Domain
- Chlorocebus aethiops
- Choline-Phosphate Cytidylyltransferase -- chemistry
- Crystallography, X-Ray
- Humans
- Lipodystrophy -- genetics
- Mutation
- Osteochondrodysplasias -- genetics
- Phosphatidylcholines -- metabolism
- Protein Binding
- Protein Folding
- Protein Stability
- Retinal Dystrophies -- genetics
- Retinitis Pigmentosa -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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