IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia. [electronic resource]
Producer: 20200114Description: 534-547 p. digitalISSN:- 1528-0020
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Class Ia Phosphatidylinositol 3-Kinase -- genetics
- DNA Mutational Analysis
- Disease Models, Animal
- Drug Resistance, Neoplasm
- Humans
- Leukemia, Lymphocytic, Chronic, B-Cell -- drug therapy
- Mice
- Mutation
- Phosphoinositide-3 Kinase Inhibitors -- pharmacology
- Receptor, IGF Type 1 -- genetics
- Treatment Outcome
- Exome Sequencing
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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