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Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity. [electronic resource] by
- Li, Hao
- Ponder, Elizabeth L
- Verdoes, Martijn
- Asbjornsdottir, Kristijana H
- Deu, Edgar
- Edgington, Laura E
- Lee, Jeong Tae
- Kirk, Christopher J
- Demo, Susan D
- Williamson, Kim C
- Bogyo, Matthew
Producer: 20130604
In:
Chemistry & biology vol. 19
Availability: No items available.
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6.
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Selective inhibition of chymotrypsin-like activity of the immunoproteasome and constitutive proteasome in Waldenstrom macroglobulinemia. [electronic resource] by
- Roccaro, Aldo M
- Sacco, Antonio
- Aujay, Monette
- Ngo, Hai T
- Azab, Abdel Kareem
- Azab, Feda
- Quang, Phong
- Maiso, Patricia
- Runnels, Judith
- Anderson, Kenneth C
- Demo, Susan
- Ghobrial, Irene M
Producer: 20100610
In:
Blood vol. 115
Availability: No items available.
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7.
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Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma. [electronic resource] by
- Kuhn, Deborah J
- Chen, Qing
- Voorhees, Peter M
- Strader, John S
- Shenk, Kevin D
- Sun, Congcong M
- Demo, Susan D
- Bennett, Mark K
- van Leeuwen, Fijs W B
- Chanan-Khan, Asher A
- Orlowski, Robert Z
Producer: 20071213
In:
Blood vol. 110
Availability: No items available.
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8.
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A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis. [electronic resource] by
- Muchamuel, Tony
- Basler, Michael
- Aujay, Monette A
- Suzuki, Erika
- Kalim, Khalid W
- Lauer, Christoph
- Sylvain, Catherine
- Ring, Eileen R
- Shields, Jamie
- Jiang, Jing
- Shwonek, Peter
- Parlati, Francesco
- Demo, Susan D
- Bennett, Mark K
- Kirk, Christopher J
- Groettrup, Marcus
Producer: 20090727
In:
Nature medicine vol. 15
Availability: No items available.
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9.
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Cellular localization and antiproliferative effect of peptides discovered from a functional screen of a retrovirally delivered random peptide library. [electronic resource] by
- Hitoshi, Yasumichi
- Gururaja, Tarikere
- Pearsall, Denise M
- Lang, Wayne
- Sharma, Poonam
- Huang, Betty
- Catalano, Susan M
- McLaughlin, John
- Pali, Erlina
- Peelle, Beau
- Vialard, Jorge
- Janicot, Michel
- Wouters, Walter
- Luyten, Walter
- Bennett, Mark K
- Anderson, Dave C
- Payan, Donald G
- Lorens, James B
- Bogenberger, Jacob
- Demo, Susan
Producer: 20040616
In:
Chemistry & biology vol. 10
Availability: No items available.
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10.
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Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome. [electronic resource] by
- Demo, Susan D
- Kirk, Christopher J
- Aujay, Monette A
- Buchholz, Tonia J
- Dajee, Maya
- Ho, Mark N
- Jiang, Jing
- Laidig, Guy J
- Lewis, Evan R
- Parlati, Francesco
- Shenk, Kevin D
- Smyth, Mark S
- Sun, Congcong M
- Vallone, Marcy K
- Woo, Tina M
- Molineaux, Christopher J
- Bennett, Mark K
Producer: 20070727
In:
Cancer research vol. 67
Availability: No items available.
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11.
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Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition. [electronic resource] by
- Jacque, Nathalie
- Ronchetti, Anne Marie
- Larrue, Clément
- Meunier, Godelieve
- Birsen, Rudy
- Willems, Lise
- Saland, Estelle
- Decroocq, Justine
- Maciel, Thiago Trovati
- Lambert, Mireille
- Poulain, Laury
- Hospital, Marie Anne
- Sujobert, Pierre
- Joseph, Laure
- Chapuis, Nicolas
- Lacombe, Catherine
- Moura, Ivan Cruz
- Demo, Susan
- Sarry, Jean Emmanuel
- Recher, Christian
- Mayeux, Patrick
- Tamburini, Jérôme
- Bouscary, Didier
Producer: 20151204
In:
Blood vol. 126
Availability: No items available.
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12.
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Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer. [electronic resource] by
- Gross, Matt I
- Demo, Susan D
- Dennison, Jennifer B
- Chen, Lijing
- Chernov-Rogan, Tania
- Goyal, Bindu
- Janes, Julie R
- Laidig, Guy J
- Lewis, Evan R
- Li, Jim
- Mackinnon, Andrew L
- Parlati, Francesco
- Rodriguez, Mirna L M
- Shwonek, Peter J
- Sjogren, Eric B
- Stanton, Timothy F
- Wang, Taotao
- Yang, Jinfu
- Zhao, Frances
- Bennett, Mark K
Producer: 20141209
In:
Molecular cancer therapeutics vol. 13
Availability: No items available.
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13.
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Design and synthesis of an orally bioavailable and selective peptide epoxyketone proteasome inhibitor (PR-047). [electronic resource] by
- Zhou, Han-Jie
- Aujay, Monette A
- Bennett, Mark K
- Dajee, Maya
- Demo, Susan D
- Fang, Ying
- Ho, Mark N
- Jiang, Jing
- Kirk, Christopher J
- Laidig, Guy J
- Lewis, Evan R
- Lu, Yan
- Muchamuel, Tony
- Parlati, Francesco
- Ring, Eileen
- Shenk, Kevin D
- Shields, Jamie
- Shwonek, Peter J
- Stanton, Timothy
- Sun, Congcong M
- Sylvain, Catherine
- Woo, Tina M
- Yang, Jinfu
Producer: 20090602
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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14.
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The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma. [electronic resource] by
- Momcilovic, Milica
- Bailey, Sean T
- Lee, Jason T
- Fishbein, Michael C
- Braas, Daniel
- Go, James
- Graeber, Thomas G
- Parlati, Francesco
- Demo, Susan
- Li, Rui
- Walser, Tonya C
- Gricowski, Michael
- Shuman, Robert
- Ibarra, Julio
- Fridman, Deborah
- Phelps, Michael E
- Badran, Karam
- St John, Maie
- Bernthal, Nicholas M
- Federman, Noah
- Yanagawa, Jane
- Dubinett, Steven M
- Sadeghi, Saman
- Christofk, Heather R
- Shackelford, David B
Producer: 20190227
In:
Cancer cell vol. 33
Availability: No items available.
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15.
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Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. [electronic resource] by
- Momcilovic, Milica
- Bailey, Sean T
- Lee, Jason T
- Fishbein, Michael C
- Magyar, Clara
- Braas, Daniel
- Graeber, Thomas
- Jackson, Nicholas J
- Czernin, Johannes
- Emberley, Ethan
- Gross, Matthew
- Janes, Julie
- Mackinnon, Andy
- Pan, Alison
- Rodriguez, Mirna
- Works, Melissa
- Zhang, Winter
- Parlati, Francesco
- Demo, Susan
- Garon, Edward
- Krysan, Kostyantyn
- Walser, Tonya C
- Dubinett, Steven M
- Sadeghi, Saman
- Christofk, Heather R
- Shackelford, David B
Producer: 20171213
In:
Cell reports vol. 18
Availability: No items available.
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