Direct Inhibitory Effect of the PDE4 Inhibitor Roflumilast on Neutrophil Migration in Chronic Obstructive Pulmonary Disease. [electronic resource]
Producer: 20191218Description: 445-453 p. digitalISSN:- 1535-4989
- Aminopyridines -- pharmacology
- Benzamides -- pharmacology
- CD11b Antigen -- metabolism
- Calcium -- metabolism
- Chemokine CXCL1 -- metabolism
- Chemotaxis, Leukocyte -- drug effects
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Cyclic Nucleotide Phosphodiesterases, Type 4 -- metabolism
- Cyclopropanes -- pharmacology
- Guanine Nucleotide Exchange Factors -- metabolism
- Humans
- Leukotriene B4 -- metabolism
- Neutrophils -- metabolism
- Phosphodiesterase 4 Inhibitors -- pharmacology
- Pulmonary Disease, Chronic Obstructive -- pathology
- Rolipram -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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