Cysteine 98 in CYP3A4 contributes to conformational integrity required for P450 interaction with CYP reductase. [electronic resource]
Producer: 20061127Description: 42-54 p. digitalISSN:- 0003-9861
- Amino Acid Substitution
- Binding Sites
- Cysteine -- chemistry
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- chemistry
- Enzyme Activation
- Enzyme Stability
- Mutagenesis, Site-Directed
- NADPH-Ferrihemoprotein Reductase -- chemistry
- Protein Binding
- Protein Conformation
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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