Methotrexate Locally Released from Poly(e-Caprolactone) Implants: Inhibition of the Inflammatory Angiogenesis Response in a Murine Sponge Model and the Absence of Systemic Toxicity. [electronic resource]
Producer: 20171010Description: 3731-42 p. digitalISSN:- 1520-6017
- Acetylglucosaminidase -- metabolism
- Angiogenesis Inhibitors -- administration & dosage
- Animals
- Anti-Inflammatory Agents -- administration & dosage
- Cell Proliferation
- Collagen -- chemistry
- Drug Delivery Systems
- Drug Implants
- Drug Liberation
- Inflammation -- drug therapy
- Interleukin-6 -- metabolism
- Macrophages -- drug effects
- Male
- Methotrexate -- administration & dosage
- Mice
- Mice, Inbred BALB C
- Neovascularization, Pathologic -- drug therapy
- Neutrophil Infiltration -- drug effects
- Peroxidase -- metabolism
- Polyesters -- chemistry
- Tissue Distribution
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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