1,4-Anthraquinone: an anticancer drug that blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of L1210 leukemic cells in the same nanomolar range as daunorubicin in vitro. [electronic resource]
Producer: 20001207Description: 339-52 p. digitalISSN:- 0959-4973
- Animals
- Anthraquinones -- pharmacology
- Antibiotics, Antineoplastic -- pharmacology
- Biological Transport -- drug effects
- Cell Survival -- drug effects
- DNA Fragmentation -- drug effects
- DNA, Neoplasm -- drug effects
- Daunorubicin -- pharmacology
- Dose-Response Relationship, Drug
- In Vitro Techniques
- Leukemia L1210 -- drug therapy
- Mitosis -- drug effects
- Mitotic Index
- Neoplasm Proteins -- drug effects
- Nucleosides -- metabolism
- RNA, Neoplasm -- drug effects
- Tumor Cells, Cultured
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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