Synthetic analogues of the microtubule-stabilizing agent (+)-discodermolide: preparation and biological activity. [electronic resource]
Producer: 20040624Description: 749-56 p. digitalISSN:- 0163-3864
- Alkanes -- chemical synthesis
- Animals
- Antineoplastic Agents -- chemical synthesis
- Carbamates -- chemical synthesis
- Drug Screening Assays, Antitumor
- Humans
- Lactones -- chemical synthesis
- Leukemia P388
- Mice
- Microtubules -- drug effects
- Molecular Structure
- Nuclear Magnetic Resonance, Biomolecular
- Pyrones
- Stereoisomerism
- Structure-Activity Relationship
- Tumor Cells, Cultured
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Publication Type: Journal Article
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