Reduced effect of propofol at human {alpha}1{beta}2(N289M){gamma}2 and {alpha}2{beta}3(N290M){gamma}2 mutant GABA(A) receptors. [electronic resource]
Producer: 20100414Description: 472-81 p. digitalISSN:- 1471-6771
- Amino Acid Sequence
- Anesthetics, Intravenous -- pharmacology
- Animals
- Dose-Response Relationship, Drug
- Drug Synergism
- Female
- Humans
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oocytes -- metabolism
- Patch-Clamp Techniques
- Point Mutation
- Propofol -- pharmacology
- Rats
- Receptors, GABA-A -- drug effects
- Sequence Alignment
- Xenopus laevis
- gamma-Aminobutyric Acid -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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