The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. [electronic resource]
Producer: 20041216Description: 629-38 p. digitalISSN:- 1568-7864
- 4-Nitroquinoline-1-oxide -- adverse effects
- Adenine -- analogs & derivatives
- Alkylating Agents -- adverse effects
- Antineoplastic Agents -- adverse effects
- Apoptosis -- drug effects
- Camptothecin -- adverse effects
- Carcinogens -- adverse effects
- Cells, Cultured
- DNA Damage -- drug effects
- DNA Helicases -- antagonists & inhibitors
- DNA Replication -- drug effects
- Drug Resistance
- Exodeoxyribonucleases
- Fibroblasts -- cytology
- Glioma -- metabolism
- Guanine -- adverse effects
- Humans
- Hydroxyurea -- adverse effects
- Netropsin -- adverse effects
- O(6)-Methylguanine-DNA Methyltransferase -- metabolism
- Oligonucleotides, Antisense -- pharmacology
- RecQ Helicases
- Werner Syndrome
- Werner Syndrome Helicase
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
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