Targeted induction of apoptosis by chimeric granzyme B fusion proteins carrying antibody and growth factor domains for cell recognition. [electronic resource]
Producer: 20060605Description: 576-85 p. digitalISSN:- 1350-9047
- Antibodies -- administration & dosage
- Antineoplastic Agents -- administration & dosage
- Apoptosis -- drug effects
- Caspases -- metabolism
- Cell Line, Tumor
- Cell Membrane -- metabolism
- Cell Survival -- drug effects
- Chloroquine -- pharmacology
- Cytoplasmic Vesicles -- drug effects
- Dose-Response Relationship, Drug
- Drug Delivery Systems
- Endocytosis
- Enzyme Activation -- drug effects
- ErbB Receptors -- metabolism
- Granzymes
- Humans
- Inhibitory Concentration 50
- Pichia -- genetics
- Receptor, ErbB-2 -- immunology
- Recombinant Fusion Proteins -- administration & dosage
- Serine Endopeptidases -- administration & dosage
- Transforming Growth Factor alpha -- administration & dosage
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Publication Type: Journal Article
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