Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin. [electronic resource]
Producer: 19991124Description: 867-74 p. digitalISSN:- 0026-895X
- Acetylcysteine -- pharmacology
- Antineoplastic Agents -- pharmacology
- Antioxidants -- pharmacology
- Apoptosis
- Ceramides -- biosynthesis
- Daunorubicin -- pharmacology
- Drug Interactions
- Electron Transport -- drug effects
- Enzyme Activation
- Free Radical Scavengers -- antagonists & inhibitors
- Humans
- Hydrogen Peroxide -- metabolism
- JNK Mitogen-Activated Protein Kinases
- Mitochondria -- drug effects
- Mitogen-Activated Protein Kinases -- metabolism
- Pyrrolidines -- pharmacology
- Reactive Oxygen Species -- metabolism
- Sphingomyelin Phosphodiesterase -- metabolism
- Thiocarbamates -- pharmacology
- Transcription Factor AP-1 -- metabolism
- U937 Cells
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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