MPP(+)-like neurotoxicity of a pyridinium metabolite derived from haloperidol: in vivo microdialysis and in vitro mitochondrial studies. [electronic resource]
Producer: 19940310Description: 380-7 p. digitalISSN:- 0022-3565
- 1-Methyl-4-phenylpyridinium -- toxicity
- 3,4-Dihydroxyphenylacetic Acid -- metabolism
- Animals
- Brain -- drug effects
- Dopamine -- metabolism
- Haloperidol -- analogs & derivatives
- Lactates -- biosynthesis
- Lactic Acid
- Male
- Mice
- Microdialysis
- Mitochondria, Liver -- drug effects
- Nervous System -- drug effects
- Pyridinium Compounds -- toxicity
- Rats
- Rats, Wistar
- Receptors, Dopamine -- drug effects
- Receptors, Serotonin -- drug effects
- Serotonin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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