Phospho-p70S6K/p85S6K and cdc2/cdk1 are novel targets for diffuse large B-cell lymphoma combination therapy. [electronic resource]
Producer: 20090414Description: 1708-20 p. digitalISSN:- 1078-0432
- Adult
- Aged
- Aged, 80 and over
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Blotting, Western
- CDC2 Protein Kinase -- genetics
- Cell Proliferation -- drug effects
- Cyclin B -- genetics
- Cyclin-Dependent Kinases
- Drug Synergism
- Female
- Flow Cytometry
- G1 Phase -- drug effects
- Gene Expression Profiling
- Humans
- Immunoenzyme Techniques
- Lymphoma, Large B-Cell, Diffuse -- metabolism
- Male
- Middle Aged
- Neoplasm Recurrence, Local -- metabolism
- Oligonucleotide Array Sequence Analysis
- Phosphatidylinositol 3-Kinases -- genetics
- Phosphorylation -- drug effects
- Protein Kinases -- genetics
- Proto-Oncogene Proteins c-akt -- genetics
- RNA, Messenger -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Ribosomal Protein S6 Kinases, 70-kDa -- genetics
- Sirolimus -- administration & dosage
- Staurosporine -- administration & dosage
- TOR Serine-Threonine Kinases
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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