Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis. [electronic resource]
Producer: 20190924Description: 777-792.e14 p. digitalISSN:- 1528-0012
- Animals
- Antibodies, Neutralizing -- pharmacology
- Cell Death -- drug effects
- Fibroblasts -- drug effects
- Hepatic Stellate Cells -- drug effects
- Hepatitis -- genetics
- Hepatocytes -- drug effects
- Humans
- Inflammation Mediators -- metabolism
- Interleukin-11 -- antagonists & inhibitors
- Interleukin-11 Receptor alpha Subunit -- deficiency
- Liver -- drug effects
- Liver Cirrhosis, Experimental -- genetics
- Male
- Mice, Inbred C57BL
- Mice, Knockout
- Non-alcoholic Fatty Liver Disease -- genetics
- Signal Transduction -- drug effects
- THP-1 Cells
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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