Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism. [electronic resource]
Producer: 20190306Description: 963-970 p. digitalISSN:- 1476-5594
- AMP-Activated Protein Kinases -- metabolism
- Animals
- Biomarkers, Tumor
- Breast Neoplasms -- drug therapy
- Carbon -- metabolism
- Colonic Neoplasms -- drug therapy
- DNA Methylation -- drug effects
- Electron Transport Complex I -- metabolism
- Female
- Follow-Up Studies
- Gene Expression Regulation, Neoplastic -- drug effects
- Genome, Human
- Humans
- Hypoglycemic Agents -- pharmacology
- Metformin -- pharmacology
- Mice
- Mitochondria -- drug effects
- S-Adenosylhomocysteine -- metabolism
- S-Adenosylmethionine -- metabolism
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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