Monoclonal antibody Fab' fragment cross-linking using equilibrium transfer alkylation reagents. A strategy for site-specific conjugation of diagnostic and therapeutic agents with F(ab')2 fragments. [electronic resource]
Producer: 19941115Description: 220-35 p. digitalISSN:- 1043-1802
- Alkylating Agents -- chemical synthesis
- Animals
- Antibodies, Monoclonal -- chemistry
- Antibodies, Neoplasm -- chemistry
- Carcinoma, Renal Cell -- immunology
- Cross-Linking Reagents -- chemical synthesis
- Immunoconjugates -- chemistry
- Immunoglobulin Fab Fragments -- chemistry
- Iodine Radioisotopes
- Kidney Neoplasms -- immunology
- Male
- Mice
- Mice, Nude
- Tissue Distribution
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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