Synthesis and structure-activity relationship studies of small molecule disruptors of EWS-FLI1 interactions in Ewing's sarcoma. [electronic resource]
Producer: 20150310Description: 10290-303 p. digitalISSN:- 1520-4804
- Aniline Compounds -- chemical synthesis
- Antineoplastic Agents -- chemical synthesis
- Bone Neoplasms -- drug therapy
- Cell Proliferation -- drug effects
- Crystallography, X-Ray
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Indoles -- chemical synthesis
- Luciferases -- metabolism
- Models, Molecular
- Molecular Structure
- Oncogene Proteins, Fusion -- antagonists & inhibitors
- Proto-Oncogene Protein c-fli-1 -- antagonists & inhibitors
- RNA-Binding Protein EWS -- antagonists & inhibitors
- Sarcoma, Ewing -- drug therapy
- Structure-Activity Relationship
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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