EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms. [electronic resource]
Producer: 20181010Description: 461-477 p. digitalISSN:- 1476-5594
- Animals
- Cell Adhesion -- genetics
- Cell Line, Tumor
- Cell Transformation, Neoplastic -- genetics
- Cytoplasm -- genetics
- Enhancer of Zeste Homolog 2 Protein -- genetics
- Female
- Gene Expression Regulation, Neoplastic
- Gene Knockdown Techniques
- HEK293 Cells
- Humans
- Janus Kinase 2 -- genetics
- Jurkat Cells
- Methylation
- Mice
- Mice, Inbred BALB C
- Mice, Inbred NOD
- Mice, SCID
- Mutagenesis, Site-Directed
- Neoplasms -- genetics
- Nuclear Localization Signals -- genetics
- Proto-Oncogene Proteins c-vav -- metabolism
- Recombinant Proteins -- genetics
- STAT3 Transcription Factor -- genetics
- Talin -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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