Dexmedetomidine prevents remifentanil-induced postoperative hyperalgesia and decreases spinal tyrosine phosphorylation of N-methyl-d-aspartate receptor 2B subunit. [electronic resource]
Producer: 20120622Description: 427-31 p. digitalISSN:- 1873-2747
- Analgesics, Non-Narcotic -- pharmacology
- Analgesics, Opioid -- adverse effects
- Animals
- Blotting, Western
- Dexmedetomidine -- pharmacology
- Disease Models, Animal
- Hyperalgesia -- chemically induced
- Male
- Pain, Postoperative -- chemically induced
- Phosphorylation -- drug effects
- Piperidines -- adverse effects
- Rats
- Rats, Sprague-Dawley
- Receptors, N-Methyl-D-Aspartate -- metabolism
- Remifentanil
- Spinal Cord -- metabolism
- Tyrosine -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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