Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides. [electronic resource]
Producer: 20120717Description: 3945-59 p. digitalISSN:- 1520-4804
- Adhesins, Escherichia coli
- Animals
- Bacterial Adhesion -- drug effects
- Biofilms -- drug effects
- Biphenyl Compounds -- chemical synthesis
- Fimbriae Proteins -- antagonists & inhibitors
- Hemagglutination Inhibition Tests
- Mannosides -- chemical synthesis
- Mice
- Structure-Activity Relationship
- Urinary Tract Infections
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Publication Type: Journal Article; Research Support, American Recovery and Reinvestment Act; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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