Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion. [electronic resource]
Producer: 20180330Description: E7778-E7787 p. digitalISSN:- 1091-6490
- Animals
- Cell Line
- Glycolysis
- HEK293 Cells
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- genetics
- Immune Evasion
- Immunity, Innate
- Indoles -- metabolism
- Leukocytes, Mononuclear -- immunology
- Lipopolysaccharides -- pharmacology
- Macrophages -- metabolism
- Mice, Inbred C57BL
- Pyruvates -- metabolism
- Trypanosoma brucei brucei -- immunology
- Trypanosomiasis, African -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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