Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations. [electronic resource]
Producer: 20100504Description: 2337-45 p. digitalISSN:- 1476-5594
- Breast Neoplasms -- etiology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Class I Phosphatidylinositol 3-Kinases
- Estrogens -- pharmacology
- Female
- Humans
- Intracellular Signaling Peptides and Proteins -- antagonists & inhibitors
- Mutation
- Phosphatidylinositol 3-Kinases -- genetics
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins c-akt -- genetics
- Signal Transduction
- TOR Serine-Threonine Kinases
- Tamoxifen -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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