Epigallocatechin-3-gallate and tetracycline differently affect ataxin-3 fibrillogenesis and reduce toxicity in spinocerebellar ataxia type 3 model. [electronic resource]
Producer: 20150709Description: 6542-52 p. digitalISSN:- 1460-2083
- Amyloid -- antagonists & inhibitors
- Animals
- Ataxin-3
- COS Cells
- Caenorhabditis elegans -- drug effects
- Caenorhabditis elegans Proteins -- chemistry
- Catechin -- analogs & derivatives
- Cell Survival -- drug effects
- Chlorocebus aethiops
- Disease Models, Animal
- Gene Expression
- Green Fluorescent Proteins -- genetics
- Humans
- Hydrogen Bonding
- Machado-Joseph Disease -- drug therapy
- Microscopy, Atomic Force
- Nerve Tissue Proteins -- chemistry
- Neuroprotective Agents -- pharmacology
- Protein Aggregates -- drug effects
- Recombinant Fusion Proteins -- chemistry
- Spectroscopy, Fourier Transform Infrared
- Tetracycline -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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