Loss of PRP4K drives anoikis resistance in part by dysregulation of epidermal growth factor receptor endosomal trafficking. [electronic resource]
Producer: 20181010Description: 174-184 p. digitalISSN:- 1476-5594
- Animals
- Anoikis -- genetics
- Biomarkers, Tumor -- deficiency
- Breast Neoplasms -- pathology
- Cell Line, Tumor
- Cell Nucleus -- metabolism
- Down-Regulation
- Endosomes -- metabolism
- Epidermal Growth Factor -- metabolism
- Epithelial Cells -- cytology
- ErbB Receptors -- metabolism
- Female
- Humans
- Lung Neoplasms -- pathology
- Mice
- Mice, Inbred C57BL
- Neoplasm Invasiveness -- pathology
- Ovarian Neoplasms -- pathology
- Protein Serine-Threonine Kinases -- deficiency
- RNA, Small Interfering -- metabolism
- Ribonucleoprotein, U4-U6 Small Nuclear -- deficiency
- Signal Transduction -- genetics
- Xenograft Model Antitumor Assays
- Zebrafish
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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