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Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition. [electronic resource] by
- Dalton, Samuel E
- Dittus, Lars
- Thomas, Daniel A
- Convery, Máire A
- Nunes, Joao
- Bush, Jacob T
- Evans, John P
- Werner, Thilo
- Bantscheff, Marcus
- Murphy, John A
- Campos, Sebastien
Producer: 20180717
In:
Journal of the American Chemical Society vol. 140
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CSAR 2014: A Benchmark Exercise Using Unpublished Data from Pharma. [electronic resource] by
- Carlson, Heather A
- Smith, Richard D
- Damm-Ganamet, Kelly L
- Stuckey, Jeanne A
- Ahmed, Aqeel
- Convery, Maire A
- Somers, Donald O
- Kranz, Michael
- Elkins, Patricia A
- Cui, Guanglei
- Peishoff, Catherine E
- Lambert, Millard H
- Dunbar, James B
Producer: 20170811
In:
Journal of chemical information and modeling vol. 56
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6.
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Selective and dual action orally active inhibitors of thrombin and factor Xa. [electronic resource] by
- Young, Robert J
- Brown, David
- Burns-Kurtis, Cynthia L
- Chan, Chuen
- Convery, Máire A
- Hubbard, Julia A
- Kelly, Henry A
- Pateman, Anthony J
- Patikis, Angela
- Senger, Stefan
- Shah, Gita P
- Toomey, John R
- Watson, Nigel S
- Zhou, Ping
Producer: 20070730
In:
Bioorganic & medicinal chemistry letters vol. 17
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The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors. [electronic resource] by
- Holmes, Ian P
- Gaines, Simon
- Watson, Steve P
- Lorthioir, Olivier
- Walker, Adam
- Baddeley, Suzanne J
- Herbert, Shane
- Egan, Danielle
- Convery, Máire A
- Singh, Onkar M P
- Gross, Jeffrey W
- Strelow, John M
- Smith, Robert H
- Amour, Augustin J
- Brown, David
- Martin, Stephen L
Producer: 20091130
In:
Bioorganic & medicinal chemistry letters vol. 19
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Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA. [electronic resource] by
- Prati, Federica
- Zuccotto, Fabio
- Fletcher, Daniel
- Convery, Maire A
- Fernandez-Menendez, Raquel
- Bates, Robert
- Encinas, Lourdes
- Zeng, Jingkun
- Chung, Chun-Wa
- De Dios Anton, Paco
- Mendoza-Losana, Alfonso
- Mackenzie, Claire
- Green, Simon R
- Huggett, Margaret
- Barros, David
- Wyatt, Paul G
- Ray, Peter C
Producer: 20190318
In:
ChemMedChem vol. 13
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Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors: Foundations for understanding inhibitor selectivity. [electronic resource] by
- Charnley, Adam K
- Convery, Máire A
- Lakdawala Shah, Ami
- Jones, Emma
- Hardwicke, Philip
- Bridges, Angela
- Ouellette, Michael
- Totoritis, Rachel
- Schwartz, Benjamin
- King, Bryan W
- Wisnoski, David D
- Kang, James
- Eidam, Patrick M
- Votta, Bartholomew J
- Gough, Peter J
- Marquis, Robert W
- Bertin, John
- Casillas, Linda
Producer: 20160907
In:
Bioorganic & medicinal chemistry vol. 23
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New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold. [electronic resource] by
- Pajk, Stane
- Živec, Matej
- Šink, Roman
- Sosič, Izidor
- Neu, Margarete
- Chung, Chun-Wa
- Martínez-Hoyos, María
- Pérez-Herrán, Esther
- Álvarez-Gómez, Daniel
- Álvarez-Ruíz, Emilio
- Mendoza-Losana, Alfonso
- Castro-Pichel, Julia
- Barros, David
- Ballell-Pages, Lluís
- Young, Robert J
- Convery, Maire A
- Encinas, Lourdes
- Gobec, Stanislav
Producer: 20161107
In:
European journal of medicinal chemistry vol. 112
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Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitors. [electronic resource] by
- Watson, Nigel S
- Brown, David
- Campbell, Matthew
- Chan, Chuen
- Chaudry, Laiq
- Convery, Máire A
- Fenwick, Rebecca
- Hamblin, J Nicole
- Haslam, Claudine
- Kelly, Henry A
- King, N Paul
- Kurtis, Cynthia L
- Leach, Andrew R
- Manchee, Gary R
- Mason, Andrew M
- Mitchell, Charlotte
- Patel, Champa
- Patel, Vipulkumar K
- Senger, Stefan
- Shah, Gita P
- Weston, Helen E
- Whitworth, Caroline
- Young, Robert J
Producer: 20060925
In:
Bioorganic & medicinal chemistry letters vol. 16
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12.
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Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides. [electronic resource] by
- Chan, Chuen
- Borthwick, Alan D
- Brown, David
- Burns-Kurtis, Cynthia L
- Campbell, Matthew
- Chaudry, Laiq
- Chung, Chun-wa
- Convery, Máire A
- Hamblin, J Nicole
- Johnstone, Lisa
- Kelly, Henry A
- Kleanthous, Savvas
- Patikis, Angela
- Patel, Champa
- Pateman, Anthony J
- Senger, Stefan
- Shah, Gita P
- Toomey, John R
- Watson, Nigel S
- Weston, Helen E
- Whitworth, Caroline
- Young, Robert J
- Zhou, Ping
Producer: 20070514
In:
Journal of medicinal chemistry vol. 50
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Structure- and property-based design of factor Xa inhibitors: pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs. [electronic resource] by
- Young, Robert J
- Campbell, Matthew
- Borthwick, Alan D
- Brown, David
- Burns-Kurtis, Cynthia L
- Chan, Chuen
- Convery, Máire A
- Crowe, Miriam C
- Dayal, Satish
- Diallo, Hawa
- Kelly, Henry A
- King, N Paul
- Kleanthous, Savvas
- Mason, Andrew M
- Mordaunt, Jackie E
- Patel, Champa
- Pateman, Anthony J
- Senger, Stefan
- Shah, Gita P
- Smith, Paul W
- Watson, Nigel S
- Weston, Helen E
- Zhou, Ping
Producer: 20070108
In:
Bioorganic & medicinal chemistry letters vol. 16
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14.
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Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs. [electronic resource] by
- Young, Robert J
- Borthwick, Alan D
- Brown, David
- Burns-Kurtis, Cynthia L
- Campbell, Matthew
- Chan, Chuen
- Charbaut, Marie
- Chung, Chun-wa
- Convery, Máire A
- Kelly, Henry A
- Paul King, N
- Kleanthous, Savvas
- Mason, Andrew M
- Pateman, Anthony J
- Patikis, Angela N
- Pinto, Ivan L
- Pollard, Derek R
- Senger, Stefan
- Shah, Gita P
- Toomey, John R
- Watson, Nigel S
- Weston, Helen E
Producer: 20080212
In:
Bioorganic & medicinal chemistry letters vol. 18
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Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs. [electronic resource] by
- Young, Robert J
- Borthwick, Alan D
- Brown, David
- Burns-Kurtis, Cynthia L
- Campbell, Matthew
- Chan, Chuen
- Charbaut, Marie
- Convery, Máire A
- Diallo, Hawa
- Hortense, Eric
- Irving, Wendy R
- Kelly, Henry A
- King, N Paul
- Kleanthous, Savvas
- Mason, Andrew M
- Pateman, Anthony J
- Patikis, Angela N
- Pinto, Ivan L
- Pollard, Derek R
- Senger, Stefan
- Shah, Gita P
- Toomey, John R
- Watson, Nigel S
- Weston, Helen E
- Zhou, Ping
Producer: 20080212
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs. [electronic resource] by
- Watson, Nigel S
- Adams, Carl
- Belton, David
- Brown, David
- Burns-Kurtis, Cynthia L
- Chaudry, Laiq
- Chan, Chuen
- Convery, Máire A
- Davies, David E
- Exall, Anne M
- Harling, John D
- Irvine, Stephanie
- Irving, Wendy R
- Kleanthous, Savvas
- McLay, Iain M
- Pateman, Anthony J
- Patikis, Angela N
- Roethke, Theresa J
- Senger, Stefan
- Stelman, Gary J
- Toomey, John R
- West, Robert I
- Whittaker, Caroline
- Zhou, Ping
- Young, Robert J
Producer: 20110705
In:
Bioorganic & medicinal chemistry letters vol. 21
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Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors. [electronic resource] by
- Haffner, Curt D
- Charnley, Adam K
- Aquino, Christopher J
- Casillas, Linda
- Convery, Máire A
- Cox, Julie A
- Elban, Mark A
- Goodwin, Nicole C
- Gough, Peter J
- Haile, Pamela A
- Hughes, Terry V
- Knapp-Reed, Beth
- Kreatsoulas, Constantine
- Lakdawala, Ami S
- Li, Huijie
- Lian, Yiqian
- Lipshutz, David
- Mehlmann, John F
- Ouellette, Michael
- Romano, Joseph
- Shewchuk, Lisa
- Shu, Arthur
- Votta, Bartholomew J
- Zhou, Huiqiang
- Bertin, John
- Marquis, Robert W
Publication details: ACS medicinal chemistry letters Nov 2019
In:
ACS medicinal chemistry letters vol. 10
Availability: No items available.
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18.
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Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs. [electronic resource] by
- Young, Robert J
- Adams, Carl
- Blows, Mike
- Brown, David
- Burns-Kurtis, Cynthia L
- Chan, Chuen
- Chaudry, Laiq
- Convery, Máire A
- Davies, David E
- Exall, Anne M
- Foster, Graham
- Harling, John D
- Hortense, Eric
- Irvine, Stephanie
- Irving, Wendy R
- Jackson, Steve
- Kleanthous, Savvas
- Pateman, Anthony J
- Patikis, Angela N
- Roethka, Theresa J
- Senger, Stefan
- Stelman, Gary J
- Toomey, John R
- West, Robert I
- Whittaker, Caroline
- Zhou, Ping
- Watson, Nigel S
Producer: 20110705
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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19.
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Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs. [electronic resource] by
- Kleanthous, Savvas
- Borthwick, Alan D
- Brown, David
- Burns-Kurtis, Cynthia L
- Campbell, Matthew
- Chaudry, Laiq
- Chan, Chuen
- Clarte, Marie-Olive
- Convery, Máire A
- Harling, John D
- Hortense, Eric
- Irving, Wendy R
- Irvine, Stephanie
- Pateman, Anthony J
- Patikis, Angela N
- Pinto, Ivan L
- Pollard, Derek R
- Roethka, Theresa J
- Senger, Stefan
- Shah, Gita P
- Stelman, Gary J
- Toomey, John R
- Watson, Nigel S
- West, Robert I
- Whittaker, Caroline
- Zhou, Ping
- Young, Robert J
Producer: 20100420
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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20.
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Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium tuberculosis InhA. [electronic resource] by
- Encinas, Lourdes
- O'Keefe, Heather
- Neu, Margarete
- Remuiñán, Modesto J
- Patel, Amish M
- Guardia, Ana
- Davie, Christopher P
- Pérez-Macías, Natalia
- Yang, Hongfang
- Convery, Maire A
- Messer, Jeff A
- Pérez-Herrán, Esther
- Centrella, Paolo A
- Alvarez-Gómez, Daniel
- Clark, Matthew A
- Huss, Sophie
- O'Donovan, Gary K
- Ortega-Muro, Fátima
- McDowell, William
- Castañeda, Pablo
- Arico-Muendel, Christopher C
- Pajk, Stane
- Rullás, Joaquín
- Angulo-Barturen, Iñigo
- Alvarez-Ruíz, Emilio
- Mendoza-Losana, Alfonso
- Ballell Pages, Lluís
- Castro-Pichel, Julia
- Evindar, Ghotas
Producer: 20140429
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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