Discovery of potent and orally bioavailable 17β-hydroxysteroid dehydrogenase type 3 inhibitors. [electronic resource]
Producer: 20120810Description: 3242-54 p. digitalISSN:- 1464-3391
- 17-Hydroxysteroid Dehydrogenases -- antagonists & inhibitors
- Administration, Oral
- Animals
- Antineoplastic Agents -- chemical synthesis
- Drug Discovery
- Drug Screening Assays, Antitumor
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- chemical synthesis
- Esters -- chemical synthesis
- HeLa Cells
- Humans
- Inhibitory Concentration 50
- Male
- Phosphates -- chemical synthesis
- Prostatic Neoplasms -- drug therapy
- Rats
- Rats, Sprague-Dawley
- Structure-Activity Relationship
- Testosterone -- blood
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Publication Type: Journal Article
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