Radiofluorinated histamine H₃ receptor antagonist as a potential probe for in vivo PET imaging: radiosynthesis and pharmacological evaluation. [electronic resource]
Producer: 20120810Description: 2889-96 p. digitalISSN:- 1464-3391
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- metabolism
- Animals
- Brain -- diagnostic imaging
- Cell Line
- Dogs
- Drug Stability
- Fluorine Radioisotopes -- chemistry
- Histamine H3 Antagonists -- chemical synthesis
- Humans
- Isotope Labeling
- Male
- Microsomes, Liver -- metabolism
- Piperidines -- chemical synthesis
- Positron-Emission Tomography
- Protein Binding
- Radiopharmaceuticals -- chemical synthesis
- Rats
- Rats, Sprague-Dawley
- Receptors, Histamine H3 -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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