Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation. [electronic resource]
Producer: 20090324Description: 1432-43 p. digitalISSN:- 1528-0020
- Animals
- Antimetabolites, Antineoplastic -- pharmacology
- Azacitidine -- analogs & derivatives
- Bacterial Infections -- genetics
- Blepharitis -- genetics
- Cell Differentiation -- drug effects
- DNA Methylation -- physiology
- Decitabine
- Genotype
- Hematopoiesis -- immunology
- Hematopoietic Stem Cells -- cytology
- Histone-Lysine N-Methyltransferase -- genetics
- Homozygote
- Mice
- Mice, Knockout
- Myeloid-Lymphoid Leukemia Protein -- genetics
- Neutrophils -- cytology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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