Low CHD5 expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer. [electronic resource]
Producer: 20150428Description: 5450-6 p. digitalISSN:- 1476-5594
- Adenocarcinoma -- metabolism
- Adult
- Aged
- Aged, 80 and over
- Biomarkers, Tumor -- metabolism
- Chemotherapy, Adjuvant
- DNA Damage -- drug effects
- DNA Helicases -- genetics
- Deoxycytidine -- analogs & derivatives
- Disease-Free Survival
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Genes, Tumor Suppressor -- drug effects
- Humans
- Kaplan-Meier Estimate
- Male
- Middle Aged
- Nerve Tissue Proteins -- genetics
- Pancreatic Neoplasms -- metabolism
- Prognosis
- Treatment Outcome
- Tumor Cells, Cultured
- Gemcitabine
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Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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