Silencing of caspase-8 in murine hepatocellular carcinomas is mediated via methylation of an essential promoter element. [electronic resource]
Producer: 20060110Description: 1602-15 p. digitalISSN:- 0016-5085
- Animals
- Base Sequence
- Carcinoma, Hepatocellular -- genetics
- Caspase 8
- Caspases -- genetics
- Cell Line, Tumor
- Consensus Sequence
- CpG Islands -- physiology
- DNA Methylation
- Epidermal Growth Factor -- genetics
- Gene Silencing
- Genes, Reporter
- Genes, myc
- Humans
- Liver Neoplasms -- genetics
- Luciferases -- genetics
- Mice
- Mice, Transgenic
- Molecular Sequence Data
- Promoter Regions, Genetic -- genetics
- Sp1 Transcription Factor -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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