An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation. [electronic resource]
Producer: 20011212Description: 3285-92 p. digitalISSN:- 0022-1767
- Animals
- CD28 Antigens -- immunology
- CD3 Complex -- immunology
- CDC2-CDC28 Kinases
- Cell Cycle
- Cell Cycle Proteins
- Cell Division
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinase 4
- Cyclin-Dependent Kinase 6
- Cyclin-Dependent Kinase Inhibitor p18
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Cytokines -- biosynthesis
- Enzyme Inhibitors -- pharmacology
- G1 Phase -- drug effects
- Immunosuppressive Agents -- pharmacology
- Lymphocyte Activation -- drug effects
- Lymphoma, T-Cell -- genetics
- Lymphoproliferative Disorders -- genetics
- Mice
- Mice, Knockout
- Mice, SCID
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins
- Receptors, Antigen, T-Cell -- immunology
- Sirolimus -- pharmacology
- T-Lymphocyte Subsets -- drug effects
- Tacrolimus -- pharmacology
- Tumor Suppressor Proteins -- deficiency
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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