The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the transition to productive infection. [electronic resource]
Producer: 20150615Description: e1004136 p. digitalISSN:- 1553-7374
- Antigens, Viral -- genetics
- Cells, Cultured
- Cytomegalovirus -- genetics
- Cytomegalovirus Infections -- genetics
- DNA-Binding Proteins -- genetics
- Down-Regulation -- genetics
- Enhancer of Zeste Homolog 2 Protein
- F-Box Proteins -- physiology
- HEK293 Cells
- HeLa Cells
- Humans
- Immediate-Early Proteins -- genetics
- Jumonji Domain-Containing Histone Demethylases -- physiology
- Polycomb Repressive Complex 2 -- physiology
- Promoter Regions, Genetic
- Signal Transduction -- physiology
- Transcription Factors -- genetics
- Viral Proteins -- genetics
- Virus Replication -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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