PML nuclear body disruption impairs DNA double-strand break sensing and repair in APL. [electronic resource]
Producer: 20171024Description: e2308 p. digitalISSN:- 2041-4889
- Animals
- Ataxia Telangiectasia Mutated Proteins -- genetics
- Cell Cycle Proteins -- genetics
- Cell Nucleus -- drug effects
- Checkpoint Kinase 2 -- genetics
- DNA -- genetics
- DNA Breaks, Double-Stranded -- radiation effects
- Disease Models, Animal
- Gamma Rays
- Gene Expression Regulation, Leukemic
- Granulocyte Precursor Cells -- drug effects
- Histones -- genetics
- Humans
- Leukemia, Promyelocytic, Acute -- genetics
- Mice
- Nuclear Proteins -- genetics
- Oncogene Proteins, Fusion -- genetics
- Signal Transduction
- Tretinoin -- pharmacology
- Tumor Suppressor p53-Binding Protein 1 -- genetics
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Publication Type: Journal Article
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