Bcl-xL anti-apoptotic network is dispensable for development and maintenance of CML but is required for disease progression where it represents a new therapeutic target. [electronic resource]
Producer: 20131210Description: 1996-2005 p. digitalISSN:- 1476-5551
- Aniline Compounds -- pharmacology
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Blast Crisis -- drug therapy
- Disease Progression
- Female
- Flow Cytometry
- Fusion Proteins, bcr-abl -- antagonists & inhibitors
- Humans
- Indoles -- pharmacology
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive -- drug therapy
- Male
- Mice
- Mice, Transgenic
- Purines -- pharmacology
- Stem Cells -- drug effects
- Sulfonamides -- pharmacology
- bcl-X Protein -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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