Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91. [electronic resource]
Producer: 20100416Description: 108-15 p. digitalISSN:- 1096-1186
- Animals
- Antineoplastic Agents, Phytogenic -- administration & dosage
- Camptothecin -- administration & dosage
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Chromatography, High Pressure Liquid
- Drug Resistance, Neoplasm
- Drug Stability
- Enzyme Inhibitors -- administration & dosage
- Female
- Half-Life
- Humans
- Injections, Intravenous
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Microsomes, Liver -- metabolism
- Neoplasms -- drug therapy
- Organosilicon Compounds -- administration & dosage
- Time Factors
- Topoisomerase I Inhibitors
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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