2-methoxyestradiol induces mitotic arrest, apoptosis, and synergistic cytotoxicity with arsenic trioxide in human urothelial carcinoma cells. [electronic resource]
Producer: 20140514Description: e68703 p. digitalISSN:- 1932-6203
- 2-Methoxyestradiol
- Aged
- Apoptosis -- drug effects
- Arsenic Trioxide
- Arsenicals -- pharmacology
- Caspases -- metabolism
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Transformed
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- DNA Fragmentation -- drug effects
- Dose-Response Relationship, Drug
- Drug Synergism
- Enzyme Activation -- drug effects
- Estradiol -- analogs & derivatives
- Female
- Histones -- metabolism
- Humans
- Mitosis -- drug effects
- Oxides -- pharmacology
- Phosphorylation -- drug effects
- Poly(ADP-ribose) Polymerases -- metabolism
- Urologic Neoplasms -- metabolism
- bcl-Associated Death Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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