Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation. [electronic resource]
Producer: 20020923Description: 30935-41 p. digitalISSN:- 0021-9258
- Androgens -- physiology
- Calcium-Calmodulin-Dependent Protein Kinases -- antagonists & inhibitors
- Cell Nucleus -- metabolism
- Chromones -- pharmacology
- Cytoskeletal Proteins -- metabolism
- Glycogen Synthase Kinase 3
- Humans
- Male
- Morpholines -- pharmacology
- PTEN Phosphohydrolase
- Phosphatidylinositol 3-Kinases -- physiology
- Phosphoric Monoester Hydrolases -- physiology
- Prostatic Neoplasms -- etiology
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins -- physiology
- Proto-Oncogene Proteins c-akt
- Trans-Activators -- metabolism
- Transcription, Genetic
- Tumor Cells, Cultured
- Tumor Suppressor Proteins -- physiology
- beta Catenin
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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