Chemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways. [electronic resource]
Producer: 20181108Description: 43639 p. digitalISSN:- 2045-2322
- Animals
- Antineoplastic Agents -- pharmacology
- Carcinoma, Hepatocellular -- genetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Disease Models, Animal
- Enzyme Inhibitors -- pharmacology
- Gene Knockdown Techniques
- Humans
- Liver Neoplasms -- genetics
- Mice
- NIMA-Interacting Peptidylprolyl Isomerase -- antagonists & inhibitors
- Proteolysis -- drug effects
- Signal Transduction -- drug effects
- Tretinoin -- pharmacology
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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