Novel promising 4-anilinoquinazoline-based derivatives as multi-target RTKs inhibitors: Design, molecular docking, synthesis, and antitumor activities in vitro and vivo. [electronic resource]
Producer: 20201021Description: 114938 p. digitalISSN:- 1464-3391
- Aniline Compounds -- chemical synthesis
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Humans
- Molecular Docking Simulation
- Molecular Structure
- Protein Kinase Inhibitors -- chemical synthesis
- Quinazolines -- chemical synthesis
- Reactive Oxygen Species -- analysis
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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