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Inhibitory effect of ketoconazole on the pharmacokinetics of a multireceptor tyrosine kinase inhibitor BMS-690514 in healthy participants: assessing the mechanism of the interaction with physiologically-based pharmacokinetic simulations. [electronic resource] by
- Yang, Zheng
- Vakkalagadda, Blisse
- Shen, Guoxiang
- Ahlers, Christoph M
- Has, Teresa
- Christopher, Lisa J
- Kurland, John F
- Roongta, Vikram
- Masson, Eric
- Zhang, Steven
Producer: 20130730
In:
Journal of clinical pharmacology vol. 53
Availability: No items available.
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Mechanistic studies on a P450-mediated rearrangement of BMS-690514: conversion of a pyrrolotriazine to a hydroxypyridotriazine. [electronic resource] by
- Hong, Haizheng
- Caceres-Cortes, Janet
- Su, Hong
- Huang, Xiaohua
- Roongta, Vikram
- Bonacorsi, Samuel
- Hong, Yang
- Tian, Yuan
- Iyer, Ramaswamy A
- Humphreys, W Griffith
- Christopher, Lisa J
Producer: 20110510
In:
Chemical research in toxicology vol. 24
Availability: No items available.
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Metabolism and disposition of [14C]BMS-690514 after oral administration to rats, rabbits, and dogs. [electronic resource] by
- Hong, Haizheng
- Su, Hong
- Sun, Haojun
- Allentoff, Alban
- Ekhato, Ihoezo V
- Chando, Theodore
- Caceres-Cortes, Janet
- Roongta, Vikram
- Iyer, Ramaswamy A
- Humphreys, W Griffith
- Christopher, Lisa J
Producer: 20101012
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 38
Availability: No items available.
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Liquid chromatography and tandem mass spectrometry method for the quantitative determination of saxagliptin and its major pharmacologically active 5-monohydroxy metabolite in human plasma: method validation and overcoming specific and non-specific binding at low concentrations. [electronic resource] by
- Xu, Xiaohui Sophia
- Demers, Roger
- Gu, Huidong
- Christopher, Lisa J
- Su, Hong
- Cojocaru, Laura
- Boulton, David W
- Kirby, Mark
- Stouffer, Bruce
- Humphreys, William G
- Arnold, Mark E
Producer: 20120717
In:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences vol. 889-890
Availability: No items available.
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