Ile481 from the guinea pig alpha-subunit plays a major role in the activation of ENaC by cpt-cAMP. [electronic resource]
Producer: 20081117Description: 101-8 p. digitalISSN:- 1421-9778
- Amino Acid Sequence
- Animals
- Cell Membrane Permeability -- drug effects
- Cyclic AMP -- analogs & derivatives
- Epithelial Sodium Channels -- chemistry
- Extracellular Space -- drug effects
- Guinea Pigs
- Ion Channel Gating -- drug effects
- Isoleucine -- metabolism
- Molecular Sequence Data
- Mutant Proteins -- metabolism
- Oocytes -- drug effects
- Perfusion
- Protein Structure, Tertiary
- Protein Subunits -- chemistry
- Sequence Alignment
- Structure-Activity Relationship
- Thionucleotides -- pharmacology
- Xenopus
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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