XL647--a multitargeted tyrosine kinase inhibitor: results of a phase II study in subjects with non-small cell lung cancer who have progressed after responding to treatment with either gefitinib or erlotinib. [electronic resource]
Producer: 20120504Description: 219-26 p. digitalISSN:- 1556-1380
- Adult
- Aged
- Aged, 80 and over
- Azabicyclo Compounds -- adverse effects
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Disease Progression
- Disease-Free Survival
- Drug Resistance, Neoplasm -- genetics
- ErbB Receptors -- genetics
- Erlotinib Hydrochloride
- Female
- Gefitinib
- Humans
- Kaplan-Meier Estimate
- Lung Neoplasms -- drug therapy
- Male
- Middle Aged
- Mutation
- Protein Kinase Inhibitors -- therapeutic use
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Quinazolines -- adverse effects
- Treatment Outcome
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Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study
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