Dual knockdown of p65 and p50 subunits of NF-kappaB by siRNA inhibits the induction of inflammatory cytokines and significantly enhance apoptosis in human primary synoviocytes treated with tumor necrosis factor-alpha. [electronic resource]
Producer: 20080926Description: 291-8 p. digitalISSN:- 0301-4851
- Apoptosis -- drug effects
- Cells, Cultured
- Cytokines -- biosynthesis
- Gene Expression Regulation -- drug effects
- Humans
- NF-kappa B p50 Subunit -- deficiency
- RNA, Small Interfering -- genetics
- Synovial Membrane -- cytology
- Transcription Factor RelA -- deficiency
- Transcription, Genetic -- genetics
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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