A-674563, a putative AKT1 inhibitor that also suppresses CDK2 activity, inhibits human NSCLC cell growth more effectively than the pan-AKT inhibitor, MK-2206. [electronic resource]
Producer: 20180525Description: e0193344 p. digitalISSN:- 1932-6203
- A549 Cells
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cyclin-Dependent Kinase 2 -- genetics
- Down-Regulation
- Gene Expression Regulation, Neoplastic -- drug effects
- Heterocyclic Compounds, 3-Ring -- pharmacology
- Humans
- Indazoles -- pharmacology
- Lung Neoplasms -- drug therapy
- Pyridines -- pharmacology
No physical items for this record
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.