Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo. [electronic resource]
Producer: 19971006Description: 1245-55 p. digitalISSN:- 0888-8809
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Carcinoma, Hepatocellular -- drug therapy
- Collagenases -- drug effects
- Desoximetasone -- analogs & derivatives
- Dose-Response Relationship, Drug
- Genes, Reporter
- Glucocorticoids -- pharmacology
- HeLa Cells -- drug effects
- Humans
- Hydroxycorticosteroids
- Immunosuppressive Agents -- pharmacology
- Interleukin-1 -- metabolism
- Male
- Mice
- Mice, Inbred Strains
- Monocytes -- drug effects
- Promoter Regions, Genetic
- Rats
- Receptors, Glucocorticoid -- drug effects
- Thymus Gland -- drug effects
- Transcription Factor AP-1 -- drug effects
- Transcriptional Activation -- drug effects
- Transfection
- Tyrosine Transaminase -- drug effects
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Publication Type: Journal Article
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