Inhibition of autophagy induced by PTEN loss promotes intrinsic breast cancer resistance to trastuzumab therapy. [electronic resource]
Producer: 20170201Description: 5445-54 p. digitalISSN:- 1423-0380
- Animals
- Autophagy -- drug effects
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- genetics
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Mice
- Microtubule-Associated Proteins -- biosynthesis
- PTEN Phosphohydrolase -- genetics
- RNA-Binding Proteins -- biosynthesis
- Receptor, ErbB-2 -- genetics
- Signal Transduction
- TOR Serine-Threonine Kinases -- biosynthesis
- Trastuzumab -- administration & dosage
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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