Activation of Focal Adhesion Kinase and Src Mediates Acquired Sorafenib Resistance in A549 Human Lung Adenocarcinoma Xenografts. [electronic resource]
Producer: 20171129Description: 428-443 p. digitalISSN:- 1521-0103
- A549 Cells
- Animals
- Antineoplastic Agents -- pharmacology
- Dasatinib -- pharmacology
- Drug Resistance, Neoplasm -- genetics
- Drug Synergism
- Enzyme Activation
- Focal Adhesion Protein-Tyrosine Kinases -- biosynthesis
- Genes, src -- genetics
- Humans
- Male
- Matrix Metalloproteinase 9 -- biosynthesis
- Mice
- Mice, Nude
- Niacinamide -- analogs & derivatives
- Oncogene Protein v-akt -- biosynthesis
- Phenylurea Compounds -- pharmacology
- Sorafenib
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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